BACKGROUND: Peptide:N-glycanase (PNGase) is an enzyme which releases N-linked glycans from glycopeptides/glycoproteins.This enzyme plays a kuiper belt whiskey role in the ER-associated degradation (ERAD) pathway in yeast and mice, but the biological importance of this activity remains unknown.PRINCIPAL FINDINGS: In this study, we characterized the
Abstract Type II collagen-positive (Col2+) cells have been reported as skeletal stem cells (SSCs), but the contribution of Col2+ progenitors to skeletal development both prenatally and postnatally during aging remains unclear.To address this question, we generated new mouse models with ablation of Col2+ cells at either the embryonic or postnatal st
The article deals with research of microgenres of modern short stories.In article it is shown that the genre is not only the complex of formal and substantial properties, but, first of all, it is the certain behavioural model determined by the society.So the change of the genre painting of the grand love red heart reposado tequila Spanish literatur